DPI Apexfill Bio has high opacity (Equivalent to 3 mm of the Aluminum or more in thickness, providing an excellent radiographic view. Particle size of less than 5 provides thin (>50 ) thickness, allowing the complete setting of gutta[1]percha, as well as cement penetration into the dentinal tubules. The release of Calcium ions is fundamental for the biological and chemical action of a filling cement. DPI Apexfill Bio presents constant release of Calcium to the tissues, promoting biomineralization and stimulation of the tissues for their fast regeneration.